You will no doubt see a child with anaphylaxis in the Emergency Department. Recognition, management and disposition are all key questions that feel incredibly fluid at this juncture. I had the pleasure of interviewing Tim Dribin, an Emergency Medicine Attending from Cincinnati Children’s who recently published a paper in PLUS ONE focusing on admissions for children with anaphylaxis. Should we move the observation time from four to two hours? Who is most at risk for biphasic reaction? And how can we use data form kids that were admitted, and received no interventions, to inform practice in the ED?