As soon as you can I would recommend you read the following post from Andrew Tagg and Don’t forget the bubbles – The fantastic Australian pediatric blog.

It reviews the recent paper from Mahajan et al from The Journal of Pediatrics and was a planned secondary analysis of an earlier PECARN study. The aim is to answer the following question: In well-appearing febrile children under the age of 60 days with a proven viral infection, how many also have a concomitant serious bacterial illness (SBI)?

Ultimately the big conclusions from the study, as well as many of the limitations are well spelled out in the DFTB post. Read it now!

Don’t Forget the Bubbles: One Way or Another / Bacterial Co-Infection


Mahajan P, Browne LR, Levine DA, Cohen DM, Gattu R, Linakis JG, Anders J, Borgialli D, Vitale M, Dayan PS, Casper TC. Risk of Bacterial Coinfections in Febrile Infants 60 Days Old and Younger with Documented Viral Infections. The Journal of pediatrics. 2018 Sep 6.