Bronchiolitis Part II: I’ll huff and I’ll puff and… Albuterol won’t make a difference (probably)

By |2016-12-14T12:57:06-05:00February 1st, 2013|Infectious Diseases|

Though meta-analyses and systematic reviews - see below - have shown that beta agonists may improve symptoms scores they certainly don't affect disease resolution. Thus, since clinical scores are subjective and don't necessarily correlate with objective measurements. When sensitivity analysis is used to weed out weaker studies any effects towards benefit in the meta analyses is mitigated. Thus, the AAP [...]

Bronchiolitis Part I: Let’s just get our definitions straight all right?

By |2016-12-14T12:57:06-05:00January 31st, 2013|Infectious Diseases|

According to the AAP's 2006 Clinical Practice Guideline, bronchiolitis is the most common lower respiratory tract infection (LRTI) in infants and is caused by a virus - most often RSV in 70-80%, Human metapneumovirus in 10-20%, and then assorted rogues such as Adenovirus, Rhinovirus, Parainfluenza, and Influenza pulling up the rear. Its cardinal pathophysiologic features include;[list type="check"] Acute inflammation Edema and [...]

Tamiflu – is it worth it?

By |2016-12-14T12:57:06-05:00January 11th, 2013|Infectious Diseases|

Many of you may have come across the correspondance between BMJ and Roche already regarding Tamiflu. If not, take a moment to look it over, don't worry, I'll wait. http://www.bmj.com/tamiflu/roche OK, welcome back... Here's the bottom line - the flu vaccine is still available in the community and is the best defense. The principal circulating viruses are AH3N2 and are [...]

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