Are we giving too much ondansetron?

By |2016-12-14T12:56:50-05:00December 3rd, 2014|Infectious Diseases, Pharmacology|

Next up from the top ten articles presented at the recent AAP NCE in San Diego is a retrospective observational analysis from Freedman et al. on the increasing use of ondansetron and its effects on clinic outcomes in children. Certainly many of you have written for ondansetron. I have written about ondansetron; including a Why We Do What We Do focusing on the evidence behind [...]

Are you giving asthmatics prednisone when you could be prescribing dexamethasone instead?

By |2016-12-14T12:56:50-05:00October 29th, 2014|Article Reviews, Pharmacology, Pulmonology|

When I said I would go into the top ten articles presented at the recent AAP NCE in San Diego I meant it. I plan to tackle each article and briefly review the results and try to drive home how this can impact your practice. First up, a steroid alternative for prednisone die-hards. I've you've been a PEMBlog reader for [...]

Why we do what we do: Intravenous magnesium for asthma exacerbations

By |2016-12-14T12:56:51-05:00October 11th, 2014|Pharmacology, Pulmonology, What We Do|

So you've thrown the kitchen sink at a child with a moderate to severe asthma exacerbation. And despite the large hematoma on their forehead from the concussive effect of the faucet ricocheting off their skull they've not improved. What's a clinician to do? Give intravenous magnesium sulfate, that's what you should do. Interestingly we learned that it was valuable when [...]

Briefs: Acetaminophen vs Ibuprofen – who reigns supreme?

By |2016-12-14T12:57:06-05:00January 18th, 2013|Briefs, Pharmacology, Toxicology|

Cue the Michael Buffer intro... Yes, then age old question surfaces again. This is also probably something that most of us don't think about on a regular basis. many of our patients' parents may swear by on or the other (usually Ibuprofen) but is there any evidence to support the superiority of one agent over another? Let's take a look [...]

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