Toxicology

Briefs: Cyanide poisoning

By Brad Sobolewski, MD, MEd|2017-02-23T11:04:07-05:00February 23rd, 2017|Briefs, Toxicology|

Cyanide poisoning is rare in children - but it is critical to be suspicious of it in children with smoke exposure in a structure fire.

Oh No, CO! (Re-post)

By Brad Sobolewski, MD, MEd|2017-01-03T15:57:34-05:00January 5th, 2017|Environmental, Toxicology|

Carbon monoxide poisoning mimics the flu. You will see cases of the flu. But you will also see CO poisoning if you know when to expect it. Read on for more.

Can Heroin + Fentanyl = death from rigid chest?

By Brad Sobolewski, MD, MEd|2016-12-14T12:56:36-05:00September 29th, 2016|Toxicology|

Could patients abusing heroin/fentanyl combinations be dying from acute rigid chest? One recent study says that this might be the case.

Toxicology Quick Hits

By Brad Sobolewski, MD, MEd|2016-12-14T12:56:49-05:00February 6th, 2015|Toxicology|

Courtesy of Steven Chan, one of the excellent Pediatric Emergency Medicine fellows at CCHMC, are some highlights from a toxicology talk given to the residents on the ED rotation. Activated charcoal is part of decontamination, but it doesn't work well for drugs like Iron, and [...]

PEM Blog Shorts: Diphenhydramine Poisoning

By Brad Sobolewski, MD, MEd|2014-04-22T09:54:16-04:00April 22nd, 2014|PEMBlog Shorts, Toxicology|

Check out the newest edition of PEMBlog Shorts - the focused video series - which focuses on diphenhydramine poisoning.

Briefs: Ahhh! Spiders!

By Brad Sobolewski, MD, MEd|2016-12-14T12:56:57-05:00October 31st, 2013|Briefs, Toxicology|

Happy Halloween everyone. I thought I'd "celebrate" by posting about some rare but still clinically important spider bites. The two that get the most press in United States are the black widow (Latrodectus mactans) and brown recluse (Loxosceles reclusa). Fortunately, there are only approximately 500 bytes [...]

Briefs: Pumping Iron

By Brad Sobolewski, MD, MEd|2016-12-14T12:56:58-05:00August 29th, 2013|Briefs, Toxicology|

Kids accidentally ingest medicines. In the Peds ED we are rightfully worried about opiates, BP meds, acetaminophen, and diabetes drugs (among many others) but we shouldn't overlook the potential dangers that come with iron ingestion. Let's take a look shall we? Why do humans need [...]

Briefs: Acetaminophen vs Ibuprofen – who reigns supreme?

By Brad Sobolewski, MD, MEd|2016-12-14T12:57:06-05:00January 18th, 2013|Briefs, Pharmacology, Toxicology|

Cue the Michael Buffer intro... Yes, then age old question surfaces again. This is also probably something that most of us don't think about on a regular basis. many of our patients' parents may swear by on or the other (usually Ibuprofen) but is there [...]

Oh No, CO!

By Brad Sobolewski, MD, MEd|2016-12-14T12:57:06-05:00January 7th, 2013|Toxicology|

Tis the season for flu-like symptoms. Many of you will see multiple members of the same family with the flu. But what if it isn't the flu? When should one be worried about carbon monoxide poisoning? Let's take a look at this colorless, odorless, potentially [...]

Clonidine: A member of the ‘one pill can kill club’

By Brad Sobolewski, MD, MEd|2016-12-14T12:57:06-05:00December 7th, 2012|PEM Education Sessions, Toxicology|

Pharmacology Clonidine is an imidazoline, a class of drugs that function as centrally-acting presynaptic alpha 2 agonists . Essentially clonidine acts like pushing down on the break pedal of sympathetic output thus decreasing sympathetically mediated vasoconstriction, cardiac inotropy, and chronotropy. It has rapid GI absorption and highly [...]