Timing of Repeat Epinephrine in Pediatric Anaphylaxis: How Long Should We Observe?
This 31-center study examined when children treated with epinephrine for anaphylaxis can be safely discharged. Most did not require additional epinephrine beyond 2 hours. For those with cardiovascular involvement, 4 hours may be sufficient. These findings support shorter, risk-based ED observation periods without compromising patient safety.